Hi-Sci Solutions Limited is a Biotech and a specialised CRO operating in the professional, scientific, and technical activities sector, focused on revolutionising preclinical drug delivery and development through advanced disease modeling. Our expertise spans across developing sophisticated in vitro models that replicate human disease conditions in oncology, renal diseases, cardiovascular disorders, infectious diseases, and metabolic syndromes.
Bridging the gap between lab research and real-world medicine—safer, faster, and more precise solutions for drug testing, disease modelling, and personalised healthcare.
Our Mission is to create accurate in vitro disease models that closely replicate human conditions offering unparalleled high-throughput platforms, automation, and real-time advanced imaging systems.
We envision a future where our pioneering disease modelling services would contribute to minimizing animal usage in drug testing dramatically.
Leveraging cutting-edge technologies including 3D culture systems, organoids, organ-on-chip platforms, and genetically modified models, we enhance the translational relevance of preclinical research. Through our high-throughput screening platforms combined with advanced imaging systems for real-time monitoring of cellular and molecular changes, we are accelerating the pace of drug discovery and paving the way for innovative therapeutic solutions.
We develop advanced physiologically relevant cancer models that mimic the human tumor microenvironment, enhancing the study of cancer progression and therapy response. Utilizing cutting-edge technologies—including hydrogels, organoids, and Organ-on-a-Chip systems—we recreate key mechanical forces and cellular interactions. Our customizable models integrate vascular co-culture, media flow, and tissue-specific stretching, providing a powerful platform for studying cancer cell behavior, drug efficacy, and immuno-oncology safety beyond traditional methods.
We develop advanced human-relevant models to study infectious diseases with high physiological accuracy. Using hydrogels, organoids, and Organ-on-a-Chip technology, we replicate key aspects of the human immune response and pathogen-host interactions. Our models incorporate vascular flow, immune cell integration, and tissue-specific dynamics, enabling precise investigations into disease progression, drug efficacy, and immune response. These customizable systems offer a powerful alternative to traditional models, improving translational insights for antiviral and antimicrobial therapies.
In vitro 3D cell culture models of fibrosis replicate the diseased microenvironment in conditions such as chronic kidney disease (CKD), rheumatic diseases, and cardiovascular fibrosis. These models enable the study of inflammatory signaling, extracellular matrix remodeling, and fibroblast activation. By integrating omics technologies and single-cell RNA sequencing (scRNA-seq), they provide deeper insights into cellular heterogeneity, disease progression, and drug mechanisms. This approach enhances the understanding of fibrosis-related microenvironments and improves drug efficacy assessment by capturing complex cell-cell interactions and molecular changes with high precision.
Our in vitro 3D cell culture models for inflammatory bowel disease (IBD) and Crohn’s disease replicate the gut microenvironment, enabling the study of immune responses, epithelial barrier function, and microbial interactions. By integrating omics technologies and single-cell RNA sequencing (scRNA-seq), these models provide deeper insights into cellular heterogeneity, inflammatory signaling, and drug mechanisms. This approach enhances the understanding of disease progression and improves drug efficacy assessment by capturing complex microenvironmental interactions with higher precision.